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Item List

ASCENT

A Randomized, Partially Masked, Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants With nAMD

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ASPIRE

A Phase 2b, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With Diabetic Macular Edema

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CONQUER

A Prospective, Multi-Center, Open-label, Sequential, Multiple Ascending-Dose and High Concentration Cohorts Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AM712 Following Intravitreal Administration in Patients With Neovascular Age-related Macular Degeneration.

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GARLAND

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World
Safety, Tolerability and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients with
Geographic Atrophy Secondary to Age-Related Macular Degeneration

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HONU

A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration

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ISIGHT

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT): A Multicenter, Randomized, Sham-controlled, Feasibility Device Trial.

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MAGNIFY

A Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants with Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

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NHOR

The Natural History Observation Registry (NHOR) is a world-wide registry of individuals with Macular Telangiectasia type 2, and their family members.

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PARASOL

A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

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PREGONDA

A Multi-Center, Non-Randomized, Open-Label, Multiple Ascending Dose, Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7497372 Following Intravitreal Administration in Participation with Diabetic Macular Edema

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PROTOCOL AO

This study compares Home OCT-Guided Treatment versus Treat and Extend for the management of neovascular (wet) AMD.

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RIVOLI

A phase IB, Multicenter, Randomized, Double Masked, Active Comparator-Controlled Study to investigate the biological activity, safety, tolerability, pharmacokinetics and pharmacodynamics of ro7200394 in participants with macular edema secondary to central retinal vein occlusion

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